Genomic analysis reveals the molecular basis for capsule loss in the group B Streptococcus population.
The human and bovine bacterial pathogen Streptococcus agalactiae (Group B Streptococcus, GBS) expresses a thick polysaccharide capsule that constitutes a major virulence factor and vaccine target.GBS can be classified into ten distinct serotypes differing in the chemical composition of their capsular polysaccharide.However, non-typeable strains tha